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Monday, April 30, 2012
Sunday, April 29, 2012
Wrapp Brings Social, Mobile Gifting Service To The U.S.; Partners With The Gap, H&M And Others
Wrapp, a social gifting service backed by Greylock Partners and Atomico, is crossing the pond with the U.S. launch of its mobile gift card and retail app. Wrapp, which was available previously only in the UK, Norway, Sweden and Japan, Wrapp is actually launching today with a number of U.S. retailers including Fab, Gap, H&M, Sephora, The Wall Street Journal, Wayfair, and others. As we've reported in the past, Wrapp was co-founded by Rebtel and SendIt founder Hjalmar Winbladh, Spotify founding CTO Andreas Ehn, and lets friends give, receive and redeem digital gift cards using mobile devices, and allows friends to contribute to gifts given by mutual friends. With Wrapp, which offers iPhone, Android and web apps, you sign in via your Facebook account, and you can then tap the Celebration tab on the app, browse your friends or major events, and select the person you want to send a gift card to. All available gift card offers for that friend are automatically listed.etan patz obama dog doug hutchison larry brown kevin hart thomas kinkade brewers
Friday, April 27, 2012
How To Kill That Awful Meebo Bar Forever [Internet]
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Tuesday, April 24, 2012
Lindsay Lohan Insurance Policies: Not Cheap!
Lindsay Lohan will play Elizabeth Taylor in the Lifetime biopic Liz and Dick, but not without a major insurance policy taken out by the network, reports say.
Many fans don't feel that Lindsay has what it takes to play a Hollywood legend of that stature. Lifetime clearly disagrees ... but is also covering its behind.
Producer Larry Thompson went to great lengths to insure his controversial star, E! News confirms. And yes, this happens. More often than you'd think.
"We have more than a Plan B actually," Thompson revealed, "[because] Lindsay Lohan may be the most insured actress that ever walked on a sound stage."
Ouch. Thompson declined to specify what the plan was, but man.
Thompson admitted moving the shooting from Canada to L.A. in order to "minimize some risk" with Lohan, with whom "troubled" has become synonymous.
He's quick to praise her on merit, however, noting that it was Lindsay's softer side of "vulnerability" that got her the part of the highly emotional legend.
"Even if I learn to regret it," he says, "Sitting here today I think it is still for the movie a great risk to run. [Lindsay's] really excited by the challenge"
"She has the right attitude and a noble purpose; it's not like she's going to go do a little job - the responsibility of playing Elizabeth Taylor is large."
The insurance premium on her crazy a$$: also not small.
[Photo: Pacific Coast News]
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Pain relief with PAP injections may last 100 times longer than a traditional acupuncture treatment
ScienceDaily (Apr. 23, 2012) ? Scientists at the University of North Carolina at Chapel Hill have identified a new way to deliver long-lasting pain relief through an ancient medical practice.
In an article published in the April 23 online edition of Molecular Pain, UNC researchers describe how exploiting the molecular mechanism behind acupuncture resulted in six-day pain relief in animal models. They call this new therapeutic approach PAPupuncture.
Principal investigator Mark J. Zylka, PhD, associate professor in the Department of Cell and Molecular Physiology and the UNC Neuroscience Center, said this is a promising study that moves his lab's work with prostatic acid phosphatase, known as PAP, towards translational research.
Several years ago, Zylka and members of his lab documented how injecting PAP into the spine eased chronic pain for up to three days in rodents. The only problem was PAP's delivery.
"Spinal injections are invasive and must be performed in a clinical setting, and hence are typically reserved for patients with excruciating pain," said Zylka. Though he had never received acupuncture or researched traditional Chinese medicine, Zylka said recent research showing how acupuncture relieved pain caught his eye.
"When an acupuncture needle is inserted into an acupuncture point and stimulated, nucleotides are released. These nucleotides are then converted into adenosine," said Zylka. Adenosine has antinociceptive properties, meaning adenosine can decrease the body's sensitivity to pain. The release of adenosine offers pain relief, but for most acupuncture patients that relief typically lasts for a few hours.
"We knew that PAP makes adenosine and lasts for days following spinal injection, so we wondered what would happen if we injected PAP into an acupuncture point?" Zylka said. "Can we mimic the pain relief that occurs with acupuncture, but have it last longer?"
To find out, Zylka and his lab injected PAP into the popliteal fossa, the soft tissue area behind the knee. This also happens to be the location of the Weizhong acupuncture point. Remarkably, they saw that pain relief lasted 100 times longer than a traditional acupuncture treatment. What's more, by avoiding the spine the researchers could increase the dose of PAP. A single injection was also effective at reducing symptoms associated with inflammatory pain and neuropathic pain.
"Pinning down the mechanisms behind acupuncture, at least in animal models, was critical," said Zylka. "Once you know what chemicals are involved, you can exploit the mechanism, as we did in our study."
The next step for PAP will be refining the protein for use in human trials. UNC has licensed the use of PAP for pain treatment to Aerial BioPharma, a Morrisville, N.C.-based biopharmaceutical company.
Zylka said PAP could be applicable to any area where regional anesthesia is performed to treat pain. And PAP has the potential to last longer than a single injection of local anesthetic -- the class of drugs used in regional anesthesia.
"When it comes to pain management, there is a clear need for new approaches that last for longer periods of time," said Julie Hurt, PhD, a postdoctoral fellow in Zylka's lab.
Zylka co-authored the paper with Hurt. The research was undertaken at UNC and was supported by the National Institute of Neurological Disorders and Stroke, a component of the National Institutes of Health.
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The above story is reprinted from materials provided by University of North Carolina at Chapel Hill School of Medicine, via Newswise.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Julie K Hurt, Mark J Zylka. PAPupuncture has localized and long-lasting antinociceptive effects in mouse models of acute and chronic pain. Molecular Pain, 2012; 8 (1): 28 DOI: 10.1186/1744-8069-8-28
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
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Monday, April 23, 2012
Gavin Kim's on the move again, joins NQ Mobile after leaving Windows Phone
That was quick. A mere five days after saying goodbye to his cohorts at Microsoft, former Windows Phone GM Gavin Kim has landed at Mobile NQ as its Chief Product Officer. By joining the mobile privacy and security firm, Kim will be working with a couple of former Samsung colleagues at Mobile NQ -- co-CEO Omar Khan and PR maven Kim Titus. The real question is, with this being Gavin's third career stop in a year, how long will the reunion last?
Continue reading Gavin Kim's on the move again, joins NQ Mobile after leaving Windows Phone
Gavin Kim's on the move again, joins NQ Mobile after leaving Windows Phone originally appeared on Engadget on Mon, 23 Apr 2012 18:28:00 EDT. Please see our terms for use of feeds.
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This Girl Quit Her Job at Microsoft By Singing a Song on YouTube [Video]
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Skype for Windows Phone sheds beta title, graduates to v1.0
Skype's fledgling Windows Phone app broke out of beta today, adding contact searching and landline calling to it's VOIP repertoire. The update comes just shy of two months of the Beta's introduction in February, and boasts a handful of minor improvements that should keep your calls connected. You'll still be making those calls yourself, however, as the full version doesn't yet have support for receiving calls in the background -- if the app isn't running, your phone isn't ringing. Hit the source link below to update.
Skype for Windows Phone sheds beta title, graduates to v1.0 originally appeared on Engadget on Sun, 22 Apr 2012 16:33:00 EDT. Please see our terms for use of feeds.
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